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Table 3 Distribution of SNP variations among study participants - Recessive model

From: SNP variations in IL10, TNFα and TNFAIP3 genes in patients with dry eye syndrome and Sjogren’s syndrome

SNP Risk Allele Allele SSa (n = 82) % DESb (n = 98) % P (χ2) CEUc Freq. (HapMap)
TNFα (rs1800629) G      
   G Allele 84.2 70.3   82.7
  A Allele 15.8 29.7   17.3
     0.56  
IL10 (rs1800896) A      
   G Allele 37.9 42.8   53.1
  A Allele 62.1 57.2   46.9
     0.23  
TNFAIP3 (rs2230926) G      
   T Allele 94.1 91.6   97.3
  G Allele 5.9 8.4   2.7
     0.54  
  1. a - ss (Sjogren’s Syndrome); b − DES (Dry Eye Syndrome)
  2. c − CEU (C): Utah residents with Northern and Western European ancestry from the CEPH collection. Data is available at Hapmap
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Journal of Inflammation

ISSN: 1476-9255

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